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Sr. Director, Project Management

If interested and qualified, please include Requisition # 2018-302 in the subject line when emailing resume to:

For more information on CRISPR Therapeutics, please click here.

Position Summary

We are seeking a Project Manager to drive the overall success of our R&D programs. This person will join a strong team in the Cambridge MA facility; driving the success of R&D development teams. The individual will work collaboratively with the program teams to plan, track and report the diverse activities and R&D of drug development including discovery, preclinical research, CMC and clinical manufacturing, regulatory affairs, clinical development, commercial, project strategy and finance.

This is an exciting and interdisciplinary role for a highly qualified and motivated individual. The successful candidate will be a confident project manager, with attention to detail and significant prior success in preclinical and early clinical stage program and project management in the biotechnology industry. The ideal candidate will be detail driven and have a proven track record in managing and driving project success. The successful candidate will also have experience in multiple modes of therapeutics including cell based therapy and gene therapy. We are seeking someone with a sense of urgency for developing important new medicines for devastating diseases and who is interested in forging new and uncharted paths to patients for the exciting CRISPR technology.


  • Manages program team(s) and is responsible for working closely with program team members to manage the operational aspects of the program(s), including developing overall tactical implementation plans, fully integrated program timelines and budgets. Tracks and monitors key milestones and decision points, to drive delivery of project objectives,
  • Interfaces with, and coordinates relevant functional groups to ensure timely execution of program activities including anticipating and identifying project risks, mitigations and contingencies, and supporting timely action plans and issue resolution
  • Represents and reports program to Senior Management; ensures effective communication to align program activities with corporate strategy, and ensure effective program execution
  • Fosters a culture of ownership and accountability including continuous benchmarking, evaluation, recognition and process improvement
  • Focuses operations to deliver results by influencing team members beyond existing benchmarks and their own expectations
  • Partners with finance and functional leaders to develop program budget including capability and capacity needs, and monitors spend against program budgets; develops project scenario planning for decision making
  • Ensures the development and use of key project management tools, metrics and team meeting logistics and documentation, by the Project Manager and all team members, to enhance project and program delivery and information dissemination to the business
  • Ensures effective program team meetings, logistics and documentation
  • For programs that are in alliances, drives reporting and project management with collaboration partners

Minimum Qualifications

  • 10 year’s experience in life sciences industry, with 5 years of demonstrated project management experience managing cross-functional product development efforts
  • Outstanding detailed project management skills with an integrated view of business and scientific issues, and demonstrated passion for creating new medicines
  • Advanced degree (BS, MS or MBA)
  • Ability to work independently and successfully in a matrix environment, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively
  • Proficiency in MS Office suite, including MS Project
  • Strong oral and written communication skills, a high degree of energy, accuracy and attention to detail, and a passion for delivering important new medicines to patients with devastating diseases

Preferred Qualifications

  • 10+ years’ experience in life sciences industry, with 8+ years of demonstrated program management and leadership experience managing cross-functional product development efforts
  • PMP certification
  • Experience leading gene editing or gene therapy programs


  • Results Oriented
  • Entrepreneurial Spirit
  • Undaunted
  • Communication & Teamwork

If interested and qualified, please include Requisition # 2018-302 in the subject line when emailing resume to:

For more information on CRISPR Therapeutics, please click here.